A practical Handbook for the Sizing of Normal Flow Filtration Filters

30 years of membrane filter sizing expertise in your hands: A guide for process developers in the pharmaceutical and biopharmaceutical industries. Margarete Hannappel and Coauthors

ISBN: 979-10-95285-05-2 EAN: 9791095285052

Contents:

A. Introduction

B. Membrane and Surface and Filters

  1. Filter retention mechanisms
  2. Characteristics and properties of surface and membrane filters
  3. Filter formats and devices
  4. Filter usage in bioprocessing

C. Testing and Sizing of Surface and Membrane Filters

  1. The VmaxTM filtration method
  2. How to perform a VmaxTM filtration trial
  3. How to analyse and interpret VmaxTM trial data
  4. How to scale up a process based on VmaxTM trial results
  5. Safety factors and filter scale-up considerations

D. Special Filtration Applications using Surface and Membrane Filters

  1. Impact of feed properties on filter performance and sizing
  2. Filtration of particles (viruses, VLPs, emulsions, liposomes)
  3. Serial filtration of surface and membrane filters
  4. Virus clearance filtration

E. VmaxTM formulas on one page

 

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A practical Handbook for the Sizing of Normal Flow Filtration Filters

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