A practical Handbook for the Sizing of Normal Flow Filtration Filters
30 years of membrane filter sizing expertise in your hands: A guide for process developers in the pharmaceutical and biopharmaceutical industries. Margarete Hannappel and Coauthors
ISBN: 979-10-95285-05-2 EAN: 9791095285052
Contents:
A. Introduction
B. Membrane and Surface and Filters
- Filter retention mechanisms
- Characteristics and properties of surface and membrane filters
- Filter formats and devices
- Filter usage in bioprocessing
C. Testing and Sizing of Surface and Membrane Filters
- The VmaxTM filtration method
- How to perform a VmaxTM filtration trial
- How to analyse and interpret VmaxTM trial data
- How to scale up a process based on VmaxTM trial results
- Safety factors and filter scale-up considerations
D. Special Filtration Applications using Surface and Membrane Filters
- Impact of feed properties on filter performance and sizing
- Filtration of particles (viruses, VLPs, emulsions, liposomes)
- Serial filtration of surface and membrane filters
- Virus clearance filtration
E. VmaxTM formulas on one page
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