Capsules : Fields of Application & Industrial Technologies

It takes an educational approach to various themes: specifications and fields of capsule application, industrial filling technologies, dosing systems, the specifics of film coating, troubleshooting, ect. This guide is indented for industrial users, students and young professionals, and deserves a place in all R&D and production departments.

ISBN: 979-10-95285-01-4 EAN: 9791095285014

Contents:

Part 1 – Capsule Manufacture

1. INTRODUCTION
1.1. Definition
1.2. Capsule appearance
1.3. Composition

2. SPECIFICATIONS
2.1. Dimensions, capacities
2.2. Moisture content
2.3 Disintegration time

3. CAPSULE MANUFACTURE
3.1. Manufacturing process
3.2 Manufacturing inspections

Part 2 – Fields of application

1. CAPSULE FILLING PRODUCTS

2. CAPSULES FOR SPECIFIC APPLICATIONS
2.1. Modified release
2.2. Capsules for pulmonary or nasal dispensation systems
2.3. Liquid formulations in capsules
2.4. Other technologies

3. FACING UP TO CURRENT CHALLENGES
3.1. Patient centric design
3.2. Quality by design and industrial efficiency

Part 3 – Industrial implementation

1. CAPSULE FILLING CYCLE
1.1. Orientation and opening
1.2. Filling
1.3. Closing full capsules
1.4. Ejection

2. ALTERNATING MACHINES
2.1. General work flow

3. CONTINUOUS MACHINES
3.1. Single turret principle
3.2. Multiple turret principle

4. DOSING TECHNIQUES
4.1. Powder dosing
4.2. Micropellet filling
4.3. Solid unit form filling
4.4. Micotablet filling
4.5. Liquid and semi-solid filling

5. CONTROL SYSTEMS
5.1. Individual control of powder dosing with strain gauges
5.2. Individual control of pellet dosing
5.3. Individual camera control of microtablet dosing
5.4. Actual weight inspection systems

6. INSTALLATION / CONFIGURATION OF THE CAPSULE FILLING MACHINE
6.1. Standard
6.2. Through the wall 6.3. Modular systems

7. SORTING SYSTEMS / MACHINE EXIT INSPECTION
7.1. Elimination of deformed capsules
7.2. Elimination of empty or part-filled capsules
7.3. Metal detectors

8. CONTAINMENT
8.1. Containment problem
8.2. High-containment in capsule filling
8.3. Cleaning

9. SUBSEQUENT CAPSULE PROCESSING
9.1. Sealing / wrapping
9.2. Enteric film coating

10. TROUBLESHOOTING
10.1. General
10.2. Faults and diagnosis

 

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